Differences in categorical values were also analyzed stratified by gastrointestinal pathogen infections and by diarrheal symptoms. Multinomial logistic regression models were used to determine whether vitamin A-supplemented children had different categorical values of MCP-1 compared with children in the placebo group. Values of MCP-1 were categorized into 3 levels (nondetectable, mpc essentials and acid pro 8

Stools collected during the summer months were screened for MCP-1 and gastrointestinal pathogens. Fecal MCP-1 concentrations, determined by an enzyme-linked immuno absorption assay, were compared among 127 Mexican children 5–15 mo of age randomized to receive a vitamin A supplement (<12 mo of age, 20,000 IU of retinol ≥12 mo, 45,000 IU) every 2 mo or a placebo as part of a larger vitamin A supplementation trial. Previous studies have not addressed the impact of vitamin A supplementation on the production of monocyte chemoattractant protein 1 (MCP-1), an essential chemokine involved in pathogen-specific mucosal immune response. The impact of vitamin A supplementation on childhood diarrhea may be determined by the regulatory effect supplementation has on the mucosal immune response in the gut.

Mpc essentials and acid pro 8